Obesity and Its Association with Chronic Diseases

Abstract

The epidemic of obesity has evolved into a worldwide health concern, which poses significant challenges not only to individuals but also to healthcare systems in every corner of the world. the intricate connection that exists between obesity and chronic illnesses, shedding light on the several ways in which excessive levels of adiposity can have a detrimental impact on a person's health. An abnormal buildup of body fat, which is what obesity is, has been related to a broad variety of chronic illnesses such as diabetes, heart disease, and cancer. In addition to musculoskeletal problems and some forms of cancer, these diseases include cardiovascular diseases, type 2 diabetes, hypertension, and certain types of cancer. However, this list is not exhaustive. An abnormal buildup of fat in the body is one of the defining characteristics of obesity. This intricate connection is impacted by a number of different elements, such as heredity, environment, and lifestyle, and as a consequence, it has become an essential worry for the health of the general public. These associations are caused by a number of pathophysiological processes, including chronic low-grade inflammation, insulin resistance, dyslipidemia, and dysfunctional adipokines. The accumulation of these pathophysiological processes is a factor that contributes to the development and progression of chronic disorders. In addition, the comorbidities that are linked with obesity create a major financial burden on healthcare systems. This underscores the significance of creating effective approaches for the prevention and management of obesity through increased efficiency.