Genomic Medicine: From Bench to Bedside in the Era of Precision Healthcare


  • Dr. Manish Gupta St. John's Medical College, Bengaluru



Genomic medicine, Precision healthcare, Genomic sequencing, Personalized medicine, Genetic variants


Genomic medicine represents a transformative approach to healthcare that leverages advances in genomics and bioinformatics to inform clinical decision-making and personalize medical treatments. This abstract provides an overview of the emerging field of genomic medicine, highlighting its potential to revolutionize patient care and improve health outcomes. Genomic sequencing technologies have enabled the rapid and cost-effective analysis of individual genomes, facilitating the identification of genetic variants associated with disease susceptibility, drug response, and treatment efficacy. Integration of genomic data into clinical practice holds promise for early disease detection, accurate diagnosis, and tailored therapeutic interventions. Challenges such as data interpretation, privacy concerns, and healthcare disparities must be addressed to realize the full potential of genomic medicine. Despite these challenges, genomic medicine offers unprecedented opportunities to advance precision healthcare and transform the delivery of medical services.


Collins, F. S., & Varmus, H. (2015). A new initiative on precision medicine. New England Journal of Medicine, 372(9), 793-795.

Manolio, T. A., Chisholm, R. L., Ozenberger, B., Roden, D. M., Williams, M. S., Wilson, R., ... & Ginsburg, G. S. (2013). Implementing genomic medicine in the clinic: the future is here. Genetics in Medicine, 15(4), 258-267.

Green, E. D., & Guyer, M. S. (2011). Charting a course for genomic medicine from base pairs to bedside. Nature, 470(7333), 204-213.

Hamburg, M. A., & Collins, F. S. (2010). The path to personalized medicine. New England Journal of Medicine, 363(4), 301-304.

Kohane, I. S., & Altman, R. B. (2005). Health-information altruists—a potentially critical resource. New England Journal of Medicine, 353(19), 2074-2077.

Feero, W. G., Guttmacher, A. E., & Collins, F. S. (2010). Genomic medicine—an updated primer. New England Journal of Medicine, 362(21), 2001-2011.

Ginsburg, G. S., & McCarthy, J. J. (2001). Personalized medicine: revolutionizing drug discovery and patient care. Trends in Biotechnology, 19(12), 491-496.

Ashley, E. A. (2016). Towards precision medicine. Nature Reviews Genetics, 17(9), 507-522.

Manolio, T. A., & Fowler, D. M. (2021). The promise and challenges of combining genomic and electronic health records to optimize clinical care. Nature Reviews Genetics, 22(12), 741-755.

Topol, E. J. (2019). High-performance medicine: the convergence of human and artificial intelligence. Nature Medicine, 25(1), 44-56.

Mishra, S. (2024). Healthcare Quality and Patient Safety: Investigate strategies for improving healthcare quality and patient safety within Indian hospitals, focusing on best practices and case studies. International Journal for Research Publication and Seminar, 15(1), 121–139. Retrieved from

Ritcha Saxena, Ishrat Nur Ridi, & Kevin Carnewale. (2023). Towards Inclusive Excellence: Advancing Diversity and Equity in Medical Education. International Journal for Research Publication and Seminar, 14(4), 192–203. Retrieved from

Pravin Pardhi, Shriganesha Jibhakate, Suyog Wanjari, & Tina Munje. (2023). HEALTHCARE CHAT-BOT. International Journal for Research Publication and Seminar, 14(3), 89–92. Retrieved from

Himanshu Shukla, & Shubham Shukla. (2018). Study about biofilms, Issue with the use of faucet aerator, in healthcare and it’s prevention by using laminar flow device: A review. International Journal for Research Publication and Seminar, 9(4), 45–48. Retrieved from

Dr. Anill Kumar Taneja. (2017). Study and suggestions for improvement of quality of life marginalized and socially disadvantaged segments. International Journal for Research Publication and Seminar, 8(3), 96–100. Retrieved from

Vandita Sharma. (2023). Comprehensive Study of Cloud Based Digitization in Education: Issues and Challenges. International Journal for Research Publication and Seminar, 14(2), 237–243. Retrieved from

S.Chandwani, K. (2021). Heart Disease & Diabetes Prediction using Machine Learning. International Journal for Research Publication and Seminar, 12(4), 38–43. Retrieved from

Ms Shelly. (2017). Who Benefit From Essential Drug Price Control, Need of Price Control In India -A review. Innovative Research Thoughts, 3(9), 155–163. Retrieved from

Rani, P., & langyan, B. (2018). Study of Trends And Pattern of Public Expenditure on Health in Haryana State. Innovative Research Thoughts, 4(5), 403–409. Retrieved from

Anu. (2018). The Paradigm shift in Public health: A Socio-Legal study of Public and Private Healthcare Services: Emphasis on public human. Innovative Research Thoughts, 4(4), 201–207. Retrieved from



DOI: 10.36676/ssjmra.v1.i2.13
Published: 02-07-2024

How to Cite

Dr. Manish Gupta. (2024). Genomic Medicine: From Bench to Bedside in the Era of Precision Healthcare. Shodh Sagar Journal for Medical Research Advancement, 1(2), 12–18.



Original Research Article